Resistance to last-line antibiotic makes bacteria resistant to immune system

(American Society for Microbiology) Bacteria resistant to the antibiotic colistin are also commonly resistant to antimicrobial substances made by the human body, according to a study in mBio®, the online open-access journal of the American Society for Microbiology. Cross-resistance to colistin and host antimicrobials LL-37 and lysozyme, which help defend the body against bacterial attack, could mean that patients with life-threatening multi-drug resistant infections are also saddled with a crippled immune response.

Discovery of a novel medicine for the treatment of chronic wounds

(Umea University) Every 20 seconds, a limb is lost as a consequence of a diabetic foot ulcer that does not heal. To date, medical solutions that can change this situation are very limited. In his doctoral thesis, Yue Shen from the Industrial Doctoral School and the Department of Medical Biochemistry and Biophysics at Umeå University presented a novel medicine for chronic wound treatment that may completely change the lives of millions of patients.